People

Xiaochuan Pan, PhD

Research of Professor Pan’s lab centers on physics, algorithms, and engineering underpinning tomographic imaging and its biomedical and clinical applications. Dr. Pan and his lab conduct research on advanced theory and algorithms for conventional and spectral computed tomography (CT), positron emission tomography (PET), single-photo-emission computed tomography (SPECT), and tomosynthesis especially digital breast tomosynthesis (DBT) and digital lung tomosynthesis (DLT), supported by grants from federal funding agencies such as NIH and DOD, from state funding agencies, from foundations, and from industry. In collaborating with leading researchers in the field, he and his team have worked on magnetic resonance imaging (MRI) and have also investigated emerging imaging techniques, including electron-paramagnetic resonance imaging (EPRI), phase-contrast CT, and photo-acoustic tomography (PAT), among others. In recent years, he and his team have developed programs that translate theoretical concepts and methods to biomedical application work that includes developing innovative hardware systems and workflows, enabled by advanced algorithms, with a strong emphasis on the relevance and impact of imaging technological solutions tailored to specific applications of biomedical and/or clinical significance. Dr. Pan's lab has established continuous, close clinical and industrial collaboration. Dr. Pan is a Fellow of AAPM, AIMBE, IAMBE, IEEE, OSA, and SPIE.

Dual-energy CT imaging over non-overlapping, orthogonal arcs of limited-angular ranges.
Chen B, Zhang Z, Xia D, Sidky EY, Pan X. Dual-energy CT imaging over non-overlapping, orthogonal arcs of limited-angular ranges. J Xray Sci Technol. 2021 Sep 23.
PMID: 34569984

Dual-energy CT imaging with limited-angular-range data.
Chen B, Zhang Z, Xia D, Sidky EY, Pan X. Dual-energy CT imaging with limited-angular-range data. Phys Med Biol. 2021 Sep 17; 66(18).
PMID: 34320478

High-Resolution Full-3D Specimen Imaging for Lumpectomy Margin Assessment in Breast Cancer.
Kulkarni SA, Kulkarni K, Schacht D, Bhole S, Reiser I, Abe H, Bao J, Bethke K, Hansen N, Jaskowiak N, Khan SA, Tseng J, Chen B, Pincus J, Mueller J, Schulte L, LaBomascus B, Zhang Z, Xia D, Pan X, Wietholt C, Modgil D, Lester D, Lan L, Bohara B, Han X. High-Resolution Full-3D Specimen Imaging for Lumpectomy Margin Assessment in Breast Cancer. Ann Surg Oncol. 2021 Oct; 28(10):5513-5524.
PMID: 34333705

A signal detection model for quantifying overregularization in nonlinear image reconstruction.
Sidky EY, Phillips JP, Zhou W, Ongie G, Cruz-Bastida JP, Reiser IS, Anastasio MA, Pan X. A signal detection model for quantifying overregularization in nonlinear image reconstruction. Med Phys. 2021 Jun 25.
PMID: 34169538

Directional-TV algorithm for image reconstruction from limited-angular-range data.
Zhang Z, Chen B, Xia D, Sidky EY, Pan X. Directional-TV algorithm for image reconstruction from limited-angular-range data. Med Image Anal. 2021 05; 70:102030.
PMID: 33752167

Non-convex primal-dual algorithm for image reconstruction in spectral CT.
Chen B, Zhang Z, Xia D, Sidky EY, Pan X. Non-convex primal-dual algorithm for image reconstruction in spectral CT. Comput Med Imaging Graph. 2021 01; 87:101821.
PMID: 33373973

Optimization-based algorithm for solving the discrete x-ray transform with nonlinear partial volume effect.
Chen B, Liu X, Zhang Z, Xia D, Sidky EY, Pan X. Optimization-based algorithm for solving the discrete x-ray transform with nonlinear partial volume effect. J Med Imaging (Bellingham). 2020 Sep; 7(5):053502.
PMID: 33033733

Collision-avoiding imaging trajectories for linac mounted cone-beam CT.
Davis AM, Pearson EA, Pan X, Pelizzari CA, Al-Hallaq H. Collision-avoiding imaging trajectories for linac mounted cone-beam CT. J Xray Sci Technol. 2019; 27(1):1-16.
PMID: 30400125

Estimating the spectrum in computed tomography via Kullback-Leibler divergence constrained optimization.
Ha W, Sidky EY, Barber RF, Schmidt TG, Pan X. Estimating the spectrum in computed tomography via Kullback-Leibler divergence constrained optimization. Med Phys. 2019 Jan; 46(1):81-92.
PMID: 30370544

The synergistic enhancement of silver nanocubes and graphene oxide on surface plasmon-coupled emission.
Xie KX, Xu LT, Zhai YY, Wang ZC, Chen M, Pan XH, Cao SH, Li YQ. The synergistic enhancement of silver nanocubes and graphene oxide on surface plasmon-coupled emission. Talanta. 2019 Apr 01; 195:752-756.
PMID: 30625612

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